MyBioSource.com's Rabbit Polyclonal Anti-DOPA Decarboxylase Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Rabbit Polyclonal Anti-DOPA Decarboxylase Antibody was generated using AADC, DDC, and DOPA Decarboxylase as the antigen and it reacts with Rat, and Drosophila/Arthropod.
Description
Description: Dopa decarboxylase (DDC), also known as AADC, is a homodimeric vitamin B6-dependent enzyme that catalyzes the decarboxylation of hydroxylated aromatic amino acids. DDC is expressed in the adrenal medulla and catecholaminergic neurons. It catalyzes the final step in the synthesis of the neurotransmitters dopamine and serotonin. Defects in DDC are associated with the development of schizophrenia, Parkinson's disease, and hypertension. Human DDC shares 89% aa sequence identity with mouse and rat DDC